l glutathione used for L-Glutathione Complex Glutathione is one of the

10.1016/j.devcel.2015.09.008 51 DanaiL

& Kutateladze, A

CD82 palmitoylation site mutations at Cys5+Cys74 affect EGFR internalization and metabolism through recycling pathway

Materials and methods Cell culture Human acute monocytic leukemia cells, THP1, and the mouse leukemic monocyte cell line, RAW264.7, were cultured using RPMI-1640 medium modified to exclude calcium nitrate and supplemented with 2.05 mM L-Glutamine (Gibco, C11875500BT), 10% fetal bovine serum (FBS) (ExCell, FSP500), and a 1% penicillinstreptomycin mixed solution (Abiowell, AWH0529a)

TABLE 7 compatibility test results of the inventive products at Normal temperature TABLE 8 test results of compatibility stability (II) (by area normalization) After the product is respectively compatible with 0.9% sodium chloride injection, 5% glucose injection, 10% glucose injection and water for injection, the solution is placed for 6 hours at normal temperature, except that impurity A (oxidized glutathione) in related substances is increased due to reaction with oxygen in various solvents, other indexes are not obviously changed, and various detection indexes all accord with the regulations of national standards, so that the compatibility of the product is better

Complement Ther Med