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Changes in insulin regimen including, strength, manufacturer, type, injection site or method of administration may result in the need for a change in insulin dose or an adjustment in concomitant drugs

But GLP-1s are designed for longterm use , and benefits often build gradually

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Darker or more concentrated urine, for instance, usually just indicates dehydration and resolves once a person drinks more water

Embora menos comuns, em comparao com alguns outros medicamentos para diabetes, os agonistas de GLP-1 podem causar hipoglicemia (baixos nveis de acar no sangue), especialmente quando usados em conjunto com outros medicamentos para diabetes, como a insulina ou as sulfonilureias