According to the FDA announcement, Wegovy is approved to reduce the risk of major cardiovascular events such as stroke, heart attack, and cardiovascular death in adults with overweight or obesity and existing cardiovascular disease
Mounjaro is not covered for weight loss under any line
For Crohn's patients, this data helps your doctor choose the most effective compound (semaglutide, tirzepatide, or dual-compound GLP-Squared) and anticipate which side effects you're most likely to experience, enabling proactive management
In SURMOUNT-1, the most common adverse events at the 15 mg dose included nausea (31%), diarrhea (23%), constipation (11%), and vomiting (12%)
Still, the rise in risk for stomach and/or bowels containing food or stool is troubling, the researchers said, since it brings "significant risks for missed lesions, patient dissatisfaction and procedure cancellation, with wasted resources." According to the researchers, the findings suggest the need for more research to determine if updated guidelines regarding GLP-1 use before endoscopies are needed
But there are steps you can take to make them more manageable in the meantime: 1