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Intriguingly, a post hoc analysis of a phase 2 clinical trial revealed that dulaglutide treatment resulted in reductions in apoC-III and apoB levels without impacting serum LPL level, whereas treatment with tirzepatide showed a dose-dependent increase in serum LPL activity while concurrently reducing apoC-III and apoB levels (180)

Many patients settle into a pattern of injecting early in the week and reserving any social drinking for later in the week, when drug concentrations have passed their peak

The majority of commenters supported this proposal

10.1016/j.cell.2012.03.042 60 DixonS

doi: 10.2147/JIR.S312783 137 CaoFHuangCChengJHeZ