Observational studies have tracked the effects of caloric restriction on lean, healthy individuals, and demonstrated that moderate restriction (2230% decreases in caloric intake from normal levels) improves heart function and reduces markers of inflammation (C-reactive protein, tumor necrosis factor [TNF]), risk factors for cardiovascular disease (LDL cholesterol, triglycerides, blood pressure), and diabetes risk factors (fasting blood glucose, insulin levels)
Thats exactly what makes them work for weight loss, but it also creates some nutritional challenges we need to address proactively
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A two-fold increase in the percentage of myelinated axons was recorded in DA Gsta4 compared to DA Wt during remyelination (Fig