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These findings demonstrated that pramlintide's satiety-promoting effects extend beyond diabetic populations to obese non-diabetic individuals, supporting its potential role in obesity management and informing the subsequent development of amylin-based anti-obesity therapeutics

Glia 69 , 18521881 (2021)

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Tirzepatides pharmacokinetic characteristics, including albumin-binding properties due to a C20 unsaturated di-acid acyl-chain, enables sustained receptor activation and once-weekly dosage, maximizing therapeutic effects while minimizing administration frequency [68, 69]