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Mechanical stress induces Ca 2+ influx through the mechanosensitive channel PIEZO1 [105]

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Manual screening of the 108 unique records led to the exclusion of 17 manuscripts for irrelevance, resulting in 91 studies included in the review

Several studies have indicated that significant GSH depletion (30-50%) is associated with an increased proportion of oxidized GSH in post-mortem PD substantia nigra tissues (19-21)

doi: 10.3389/fphys.2025.1623500 Received 06 May 2025 Accepted 18 July 2025 Published 06 August 2025 Volume 16 - 2025 Edited by David Sebastin, University of Barcelona, Spain Reviewed by Mi Liu, Southern Medical University, China Chidozie Okoye, University of Nigeria, Nsukka, Nigeria Updates Copyright 2025 Cao, Zhao, Xia, Shi, Zhao, Li and Jiang