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However, this outstanding accomplishment has certain unfavorable consequences, such as hypertension, nephrotoxicity, and liver toxicity (Rezzani, 2004)

Additional treatment options for bone and mineral metabolism disorders accompanying kidney disease include native vitamin D supplementation, active vitamin D/vitamin D receptor agonists (e.g., paricalcitol), and calcimimetic drugs (e.g., cinacalcet, etelcalcetide) applications [3], [88], [89]

HMGB1, high-mobility group box protein 1

Anxiety as a risk factor of Alzheimer's disease and vascular dementia