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Both medications may cause gastrointestinal side effects such as nausea, which could be additive when taken together, particularly during treatment initiation
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For simulation of NAC therapy that increases the amount of GSH, we added twice the maximum GSH concentration attained during the time period preceding APAP exposure (considering all hepatocytes in the lobule) to the GSH concentration at the time of treatment, corresponding to values used in a previous study 90
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Environmental and Lifestyle Pressures Its also important to acknowledge the impact of modern life
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