In 12 weeks, study participants who lost weight with GLP-1s or gastric bypass surgeries noted they saw at least a 20% increase in facial volume, elasticity, firmness and hydration, while experiencing a major decrease in wrinkles
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In a 2025 observational cohort, the Risk of Vestibular Disorders with Semaglutide and Tirzepatide study reported dizziness in 18% of semaglutide users compared with 10% in the control group, indicating a higher-than-baseline incidence and reinforcing the need to monitor for dose- or timing-related patterns
Thus, this evidence supports the conclusion that, in addition to rigorous lifestyle interventions, pharmacological gains must be evaluated via stratification based on specific populations and target endpoints
Increased Energy: Users feel more energetic throughout the day
Anuradha et al., 2023)