ada standards of care 2025 obesity pharmacotherapy glp-1 recommendations Indications for GLP-1/GIP RA Summary Sheet and Beyond! 2025 ADA Standards of Medical – Obesity pharmacotherapy in older adults:

The science shows we can lose significant lean mass, especially with medications like tirzepatide, making it critical to prioritize high protein intake (think 1.4-1.6g/kg daily!) and consistent resistance training to build a strong, resilient foundation for your new body

Alcohol triggers endorphin release, which activates opioid receptors and, downstream, boosts dopamine

A dosing journal or tracking app

GLP-1Rs are expressed in the heart, but it is unclear if they have a role in cardioprotection, or if they are primarily involved in the regulation of BP and heart rate (103, 104, 224)

Understanding variants in genes like GIPR and GLP1R reveals whether you're genetically predisposed to dramatic cholesterol improvements or modest gains, allowing PlexusDx providers to personalize your protocol and set realistic targets

A poorly balanced plate can leave you undernourished even if weight loss continues