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GLP-1 acts through a specific GLP-1 receptor (GLP-1R), principally expressed by cells of pancreatic islets but present also in many other target tissues, such as lung, stomach, intestine, kidney, heart, and brain tissues [14,15]

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PMID: 36462999 Contreras C et al (2017): Traveling from the hypothalamus to the adipose tissue: The thermogenic pathway

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The FTO rs9939609 variant correlates with baseline metabolic rate and fat accumulation tendency