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This connection signals the melanocytes to increase melanin synthesis

doi: 10.1016/j.neuint.2017.08.009

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Adenosine is further broken down extracellularly by adenosine deaminase to inosine and Hx ( Figure 2 ) and then removed by circulation ( In the study of normal behavior, purinergic signaling has been linked to learning and memory, sleep and arousal, locomotor activity and exploration, feeding behavior, and mood and motivation (Niklasson et al., 1983)

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