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Pi-Sunyer X, Astrup A, Fujioka K, Greenway F, Halpern A, Krempf M et al (2015) A randomized, controlled trial of 3.0 mg of liraglutide in weight management
The emergence of glucagon-like peptide-1 (GLP-1) receptor agonists represents one of the most significant advances in obesity and diabetes treatment in recent decades
In combination with healthy diet and exercise
Realworld data: A 6month clinic study found an average ~4% loss, with 42.5% reaching 5% loss
Notably, kidney and cardiovascular benefits of finerenone were apparent even in combination with SGLT2i and GLP1-RA use in secondary analyses of the FIDELIO-DKD and FIGARO-DKD trials [71, 72]
These include the hypothalamus, VTA, and nucleus accumbens
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