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In response to chronic erastin treatment, very few SKOV3 and OVCA429 cells developed the enhanced flux through the transsulfuration pathway and gradually adapted to cystine deprivation caused by system X c blockage

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the intensity of the response, over time, will be less

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at pH 5.0, approximately 80% of NaF is released within 24 hours, and its antibacterial efficacy at this pH value is significantly stronger than that of the chlorhexidine (CHX) control group