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Glucagon-like peptide-1 (GLP-1) receptor agonists were originally developed to treat people with type 2 diabetes, entering clinical use in the mid-2000s

For the treatment-regimen estimand, the mean body weight reductions from baseline at 72 weeks were 15.0%, 19.5%, and 20.9% in the tirzepatide 5, 10, and 15 mg groups, respectively, versus 3.1% in the placebo group

Clinical trials are actively investigating GLP-1 Drugs for conditions like cardiovascular disease and liver disorders, with first approvals expected by 2025

Start low, stay low, escalate only when progress stalls

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Omzo's entity is not publicly disclosed