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Goodoory VC, Khasawneh M, Black CJ, Quigley EMM, Moayyedi P, Ford AC

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TADs are the first-line drugs for CVS prophylaxis and have been shown to reduce the duration, severity, and frequency of episodes, as well as the number of emergency room visits and hospitalizations.90 Amitriptyline, the TAD of choice, is usually started at a low dose of 25mg and is gradually increased to a target dose of approximately 100mg at night in adults

Option 3: 5mg + 3mL Bacteriostatic Water This results in a concentration of 1.67mg/mL