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GLP-1 medications send signals to the brain and gut receptors and balance cravings and improve the feeling of satiety

Clinical trials demonstrate that GLP-1 weight loss medications, when combined with lifestyle modifications, can produce 15-20% total body weight loss over 52 weeks

This indicates that patients may still experience the appetite regulation benefits of GLP-1s, even at lower doses, and the effects may be more gradual and gentler, which could be beneficial for long-term adherence

[DOI] [PubMed] [Google Scholar] 45

However, injections do require basic temperature-controlled storage before their first use

L., & Zdravkovic, M