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At position fifteen, the amino acid histidine (His) is replaced with a modified amino acid called D-Phenylalanine (D-Phe)

Myeloid compartment Monocytes/Macrophages and ASCVD Classical monocyte-derived macrophages are important in the early steps of atherogenesis as they contribute significantly to the creation of an inflammatory microenvironment

The capsule form ensures gradual absorption and systemic benefits, making it a practical and non-invasive alternative to injections

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Considering the promising results of the SURPASS and SURMOUNT trials, what additional factors or challenges must researchers address before adopting tirzepatide for conditions beyond Type 2 diabetes, such as non-alcoholic fatty liver disease (NAFLD)