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Typically, MT is found in the cytoplasm, but it can also translocate into the nucleus to safeguard DNA from damage and interact with transcription factors, which will be further elaborated on later

& Hirsch, E

81 Notably, Wnt5a, a common nonclassical Wnt pathway activator, after secretion by fibroblasts, activates the classic Wnt signalling pathway in AT2 cells and inhibits the transdifferentiation of AXIN2 + AT2 cells with stem cell activity into AT1 cells, thus maintaining the dryness of AT2 cells

Clin Chem 2000

Several commenters emphasized the benefits of enhanced patient access, physician-led team-based collaboration, and interdisciplinary coordination facilitated by virtual supervision

[PubMed] Kannengiesser K, Maaser C, Heidemann J, et al