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[5] [6] Gallbladder disease : Rapid weight loss associated with this drug class may increase the risk of cholelithiasis (gallstones) and related biliary complications

The advent and efficacy of injectable, and now oral, glucagon-like peptide-1 receptor agonists (GLP-1RAs) such as semaglutide (Ozempic/Wegovy, Novo Nordisk) or tirzepatide (Mounjaro/Zepbound, Eli Lilly and Company) has changed the weight loss landscape forever

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(1998) Melanocortin peptides and receptor signalling Hruby et al

Control 19 , 716723 (1974)