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Notably, certain commensals, like Clostridium cluster XIVa and segmented filamentous bacteria, have the ability to push the host immune system toward regulatory responses via regulatory Treg expansion and IL-10 production (Touchefeu et al., 2014)

Biochimica et Biophysica Acta , 1853 (5), 121928

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Quite remarkably, in those with low POP levels, the typically robust association between diabetes and obesity was not observed in a nested case-controlled study, suggesting that obesity may exaggerate the metabolic disturbances caused by POPs (perhaps because adipose tissue provides a reservoir for fat-soluble toxins), rather than being directly responsible for the altered metabolism