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The differentiation of adipose precursor cells consists of two stages, the former stage is the differentiation of adipose precursor cells into immature adipocytes, and the latter stage is the transformation of immature adipocytes to mature adipocytes, which associated genes include PPAR, C/EBP, adipocyte fatty acid-binding protein (AP2), lipoprotein lipase (LPL), etc

Vajdi, M., Safaei, E., Moeinolsadat, S., Mousavi, S., Seyedhosseini-Ghaheh, H., Abbasalizad-Farhangi, M., & Askari, G

Sci Transl Med 2020;12:eaay8071.ArticlePubMedPMC 105

Rosenstock J, Perkovic V, Johansen OE, Cooper ME, Kahn SE, Marx N, et al

Identify potential risks early in development: Request a Forced Degradation Study Common Degradation Products Observed in GLP-1 Drugs LC-HRMS studies of semaglutide and liraglutide have shown that buffer composition, pH levels, and storage temperature can strongly influence degradation pathways

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