The efficacy of liraglutide on weight management was subsequently surpassed by semaglutide, which, when administered weekly at a dose of 2.4 mg in obese patients without diabetes, resulted in a weight reduction of 12.4% compared to placebo in the STEP 1 study [46], and a reduction of 9.4% compared to liraglutide 3.0 mg in the STEP-8 study [47]
And unlike a gym membership, there is no PMPM overhead, prior authorization process, or pissed off employees eating up HR time and budget
Over the past few years, there has been an increasing discussion about the potential cardiovascular benefits of sodium-glucose cotransporter 2 inhibitors (SGLT2Is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs)
Like any other payer or employer whos bearing that cost, we want to be extremely responsible, Brian Caveney, its chief medical and scientific officer, told HR Brew in February
Conversely, for women with polycystic ovary syndrome (PCOS) or obesity-related menstrual irregularities, weight loss can actually restore ovulatory cycles and improve period regularity
Some patients find that weaning off tirzepatide is harder than semaglutide due to the dual receptor mechanism
