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(39407841) This condition is likely underdiagnosed and underreported due to limited access to diagnostic testing

Providers need to discuss options and insurance coverage

It is believed to work through several pathways: Blocking voltage-dependent sodium channels , reducing neuronal excitability Enhancing GABA (gamma-aminobutyric acid) activity , an inhibitory neurotransmitter Antagonising glutamate receptors , further dampening excitatory neurotransmission Inhibiting carbonic anhydrase enzymes , though the clinical significance of this effect varies Topiramate is taken orally, typically once or twice daily

Blood sampling and storage were similar to those used for the captive khulans

Speak to your physician if you: Are you managing any pre-existing clinical concerns

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