semaglutide vs dapagliflozin Comparative Cardiovascular Effectiveness of Glucagon-Like Peptide 1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors in Diabetes Mellitus Hemoglobin A1C change among participants

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The STEP trials demonstrated that semaglutide produces weight loss averaging 1522% over 68 weeks, while the SURMOUNT trials showed tirzepatide achieves 2022% weight reduction