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319 (7202): 1046 Greene DA, Arezzo JC, Brown MB, et al

The regulatory framework assumes compounding serves patients with legitimate customization needs, not those seeking lower-cost alternatives to branded medications

Similarly, anxiety, rapid heartbeat, or tremors might suggest over-replacement

There is a GIPR small molecule antagonist (Pfizer, PF-07976016) in phase 2 clinical trials (NCT06717425) but little information is currently available regarding its structure, in vitro profile, or in vivo efficacy

Lee H, Kim B, Choi YH, Hwang Y, Kim DH, Cho S, et al