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GLP-1 receptor agonists like semaglutide work by slowing stomach emptying and signaling fullness to your brainbut these effects stop within days of your last dose

Vitamin B12 plays a critical role in energy production and metabolism, helping to boost energy levels, support metabolic functions, and improve the efficiency of fat metabolism

Clinicians should assess each patients needs individually when deciding whether to prescribe GLP-1 receptor agonists, but based on our findings, there is no indication that the treatment poses an increased risk of suicidality in adolescents with obesity. Kerem said the findings reveal the need for future studies to examine the impact of GLP-1 receptor agonist on psychiatric measures

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Studies in animals and in human cells have suggested these compounds could improve metabolism and reduce fat absorption from the gut