gliotoxin and glutathione Regulation of Nonribosomal Peptide Synthesis: bis-Thiomethylation Attenuates Biosynthesis in Aspergillus fumigatus Gliotoxin - an overview |

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Observations further propose that it might decrease iron release from ferritin, which could reduce oxidative activity within damaged tissue environments

, Farrokhsiar, P

Studies in cultured hepatocytes and in vivo

Furthermore, a lower dose of NAC (20 mm) did not increase mucosal GSH levels and failed to reduce the injury of TNBS+ethanol-treated rats, further supporting that the protection of a high dose of NAC against TNBS+ethanol induced damage was related to the increased GSH levels