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Low fluorescent R6G signal could be detected in the cytoplasm of brain endothelial cells that received 3-PLG-dopa or 3-PLG-ibu as compared to the high signal intensive in the dual-targeted dopamine- or ibuprofen-coupled nanocarrier groups (Fig

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Using 1 H- and 19 F-NMR spectroscopy as well as gel permeation chromatography (Supplementary Figs