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Animal studies suggest that supplemental glycine may help counteract liver fat accumulation triggered by a high-sugar diet, normalize triglyceride and insulin levels, and increase levels of the antioxidant glutathione
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Cell, 153(6), 1194-1217
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These effects are believed to be partially mediated by enhanced BDNF signaling and reduced systemic inflammation, making BPC-157 of interest not only for physical injury recovery, but also for patients experiencing chronic stress, anxiety, or medication-induced neuroinflammation
This was one of the first works to demonstrate that crosstalk between astrocytes and microglia is an important regulator of the glial reactivity state
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