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Additionally, the absence of IGF-1 stimulation distinguishes it from growth hormone therapies

Inject the dose as planned and watch for reduced effectiveness over the next 48 hours

Research backs up both sides of it: a study in the Journal of Strength and Conditioning Research found free weight squats produced meaningfully higher muscle activation in the calves, hamstrings, and inner quads compared to Smith machine squats, since the stabilizing muscles have to work harder when the bar isn't guided

It did just that, with DellaVecchia losing 30 pounds between August 2022 and February 2023

doi: 10.1016/S0015-0282(16)53570-5

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