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Compound versions of some weight loss drugs to be restricted Most compounded versions of popular drugs used for weight loss including Wegovy and Zepbound may soon no longer be available after a U.S

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Secondary prevention of CVD (adults) To reduce the risk of major adverse CV events (CV death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established CV disease and either obesity or overweight WEIGHT LOSS IN ADULTS RCT STEP 1 Study - Wegovy vs Placebo for Weight Loss in Adults Without Diabetes, NEJM (2021) [PubMed abstract] The STEP 1 study enrolled 1961 overweight or obese adults without diabetes Main inclusion criteria Age 18 years 1 failed attempt at dieting BMI 30 or 27 with one weight-related condition (e.g