As for W303-1b/gsh1/pro1 or W303-1b/gsh1/proB, the overexpression of introduced Pro1 or ProB under the control of strong constitutive GAP promoter might allow a small amount of GSH in the host strains conferring tolerance to oxidative stress
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Since then, the number has progressively risen, increasing to over a billion in 2009, and remaining above 900 million in 2010
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