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Unlike caloric restriction alone, which often results in both fat and muscle loss, the peptides mechanism specifically targets adipose tissue without promoting protein catabolism

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The bulk of data sits in rodent models, with the brain-gut axis as the theoretical framework that connects the peripheral and central effects

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You're in a caloric deficit, recovery is impaired

However, the body weight of 5A-1MQ-treated obese mice (WD/LD-T group), which was indistinguishable from the other DIO groups at study start, was indistinguishable from the lean control (LD/LD-V) group at study completion (results with FDR correction