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GLP-1 receptor agonists mimic a natural gut hormone that regulates blood sugar, slows gastric emptying, and reduces appetite through central and peripheral mechanisms
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As the competition for powerful weight loss efficacy intensifies, Roche has put forward a combination strategy using an amylin analogue to address the most significant weakness of glucagon-like peptide-1 (GLP-1) class therapies: nausea as a side effect
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