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Thats 890 million adults 18 and older, and 160 million children and adolescents ages 5 to 19

doi: 10.1126/science.aan5931 12 LiCYuSLiXCaoYLiMJiGet al

However, direct dermatologic effects remain unproven

However, severe symptoms should never be ignored or treated as an unavoidable price of weight loss

Another 2025 review in the European Journal of Medical Research looked at berberine's anti-obesity impact and found that several human and animal studies linked the compound with weight loss

Drugs like Wegovy, Ozempic, and Zepbound have helped thousands of people lose weight, improve their health, and feel more confident in their daily lives