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Also in 2005, the mRNA-sequence of the equine psoriasin (a calcium-binding protein of the S100-protein family with antimicrobial activities [38]) was described and the gene was mapped to equine chromosome 5 [39]

54 Therefore, although we found that cinchonine lowered blood glucose and ameliorated NASH by activating GLP-1R, it cannot be excluded that it has other mechanisms to enhance or attenuate these effects