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In 4.2 / mice, we further confirmed that mitapivat improved the duodenal oxidative or hypoxic intracellular environment resulting in a reduction of iron uptake due to downregulation of Dmt1 expression, as evidenced by reduced (a) c-duodenum iron accumulation

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Up-regulated expression of WNT5a increases inflammation and oxidative stress via PI3K/AKT/NF-kappaB signaling in the granulosa cells of PCOS patients

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