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Management of associated conditions is essential: Diabetes control : Pioglitazone and GLP-1 receptor agonists (such as liraglutide or semaglutide) show hepatic benefits in clinical trials, but their use for NASH is off-label in the UK and should be initiated and monitored by specialists after careful riskbenefit discussion

In February 2007, Novartis received an approval letter from the FDA for vildagliptin (Galvus), another DPP-4 inhibitor

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Common side effects of semaglutide weight loss include nausea, diarrhea, and abdominal discomfort

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It is also reported that T4 improved the 72-h survival rate of mice in septic shock and reduced levels of inflammatory cytokines (TNF- and IL-1)