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Kaur and Misra 2024)
The KD is now being actively explored by a number of research groups as a potentially therapeutic approach not only for alcohol use disorders [193,194,195] but for other substance use disorders as well [196]
Claudin-5 downregulation has been shown to lead to increased BBB permeability following hypoxia, 35 focal cerebral cooling, 36 and ischemia reperfusion injury
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The regulation of diverse transcription factors, receptors for growth factors (including FGFR2b, FGFR2c, EGFR and HER2), and the activation of Akt are other elements in the reversion of MET [24]
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