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These TF act as epigenetic regulators of chromatin structure through interactions with histone modifiers, chromatin remodeling complexes, transcriptional regulators, and/or DNA methylation machinery that modulate gene expression

What the science says: A systematic review in Nutrients (2020) found that multivitamin use reduces deficiencies in adults, particularly for vitamin D, B12, and folate [11]

The addition of exogenous melatonin improves the intestinal microbial composition and circadian rhythm in high-fat diet-fed mice, thereby regulating the hosts metabolic circadian clock and lipid metabolism [57]

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3, 2021 [7] A

Dixon LK, Stahl K, Jori F, Vial L, Pfeiffer DU