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2021 Jul 29;10(8):1220.

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Together, these data demonstrate that FN-mediated MEK/ERK activation counteracts MITF nuclear accumulation and melanin synthesis, suggesting that MEK/ERKpotentially downstream of FAK act as negative regulators of melanogenesis in response to ECM cues

Oxidative DNA Damage in Lesions Relative to Dietary Intake High-fat diet induces lipid accumulation in non-adipose tissues, which can lead to oxidative stress and DNA damage (Hotamisligil and Davis, 2016

Maintain adequate protein intake to support collagen synthesis and tissue repair processes

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