Medication adjustment: If gastrointestinal side effects are contributing to back discomfort, discuss with your healthcare provider about slowing the titration schedule or temporarily holding at a lower dose until adaptation occurs
While the epigenetic link is biologically plausible and supported by early evidence, more studies are needed to confirm if GLP-1 drugs truly act on addiction-related epigenetic changes, and how long these effects last
Burgmaier M, Liberman A, Mllmann J, Kahles F, Reith S, Lebherz C, et al
F., Schmidt, W
Moreover, mean 24-h heart rate during the chamber stay was higher with both liraglutide 1.8 mg (778 beats per min
If gastrointestinal symptoms become severe, temporarily returning to the last tolerated dose followed by more gradual re-escalation may be appropriate