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25, June 2018, pp
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Clin Ther 33
They also create more opportunities for missed doses
[2] In DIO mice, 5-Amino-1MQ was reported to reduce body weight and white adipose mass and to lower plasma cholesterol, without a measured change in food intake
Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone
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