That said, here are some groups of people who are typically not candidates for semaglutide or advised to use it with caution: History of Pancreatitis Individuals with a history of pancreatitis, which is inflammation of the pancreas, should avoid semaglutide due to the potential risk of exacerbating the condition
Resistance training: Non-negotiable for muscle Peptides can support muscle preservation, but they can't replace resistance training
On the flip side, if your goal revolves around muscle maintenance or slight weight gain, your protein needs might inch towards the upper end of that spectrum
Sources Wilding JPH et al
How I Microdose GLP-1s in My Practice Heres a simplified version of how I typically guide patients through microdosing: Note: Tirzepatide microdosing follows a similar philosophy but with slightly different increments
The GLORY-2 trial showed mazdutide 9mg achieving up to 20.1% weight loss in participants with obesity, making it one of the most effective injectable weight loss medications currently in development