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Elevated levels of inflammatory cytokines have been observed in both peripheral and cerebrospinal fluid in patients with depression (87)

No significant elevations in cortisol or other adverse endocrine effects reported in clinical studies [2]

Jensterle, M., Kocjan, T., Kravos, N

Pegvisomant is a modified version of human GH that has a much higher half-life than GH and acts as a competitive antagonist of the GHR 42, 43

PMID: 35662448

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