Approximately 510% of APAP undergoes hepatic metabolism by cytochrome CYP 2E1, as a consequence, a highly reactive and harmful metabolite known as N -acetyl-para-benzoquinone imine (NAPQI), Fig
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So there are so many complicating factors, and I just commend you for trying to at least shed some light on this complicated issue that I think practitioners tend to simplify just because otherwise, it's too overwhelming to treat to be honest
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[DOI] [PubMed] [Google Scholar] 125.Saxena A.R., Banerjee A., Corbin K.D., Parsons S.A., Smith S.R
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