: : 14,9% 2,4 20,9% 15 68-72
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(1997) Structure 5 : 1287-1295 PubMed: 9351803 Search on PubMed DOI: Primary Citation Related Structures: 1AQV, 1AQW, 1AQX PubMed Abstract: Glutathione S-transferases (GSTs) are detoxification enzymes, found in all aerobic organisms, which catalyse the conjugation of glutathione with a wide range of hydrophobic electrophilic substrates, thereby protecting the cell from serious damage caused by electrophilic compounds
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Mechanism of Action: Glutathione is a major endogenous antioxidant produced by the cells, participating directly in the neutralization of free radicals and reactive oxygen compounds, as well as maintains exogenous antioxidants such as vitamins C and E in their active form
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