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The Endocrine Society and AACE (American Association of Clinical Endocrinology) have not yet issued specific updated clinical guidance for GLP-1 use in adults over 65 that fully addresses the body composition concerns raised in 2025-2026 research

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Vitamin C is very important in elderly people, patients with gastrointestinal problems like inflammatory bowel disease, chronic smokers, patients with food allergies, people who are taking high fat-containing foods, and people with liver diseases

therefore, WD-fed MC4R-KO mice are advantageous as a rodent MASH model owing to their ability to be established quickly

Understanding MASH: A Growing Public Health Concern MASH, previously known as nonalcoholic steatohepatitis (NASH), is a severe form of fatty liver disease characterized by fat accumulation in the liver, leading to inflammation and scarring